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| Halabi, Susan, Michiels, Stefan | ||||
| CRC Press | ||||
| 2019 | ||||
| English | ||||
| 626 pages | ||||
| 13.45 MB | ||||
[tab] [content title="Summary"] There is a growing demand for educational resources aimed at statisticians and researchers. This book aims to provide a solid foundation in the statistical design, execution, and analysis of clinical trials. It is particularly geared toward statisticians and investigators with limited experience in clinical trials who are looking to advance their careers in this field. Recent advancements in genetic and molecular technologies have transformed drug development, leading to more sophisticated clinical trials that integrate genomic studies. Innovative designs, such as basket and umbrella trials, have become prevalent in the industry. This book equips readers with the necessary background and expert guidance for innovative statistical design and analysis specifically in oncology clinical trials. **Key Features:** - Coverage of cutting-edge topics with the necessary technical context. - Case studies that provide a practical, "hands-on" learning experience. - Real-world examples of flaws in previously reported clinical trials, along with strategies to avoid these pitfalls. - Access to statistical code available on the book's website. - Contributions from internationally recognized statisticians from both academia and the pharmaceutical industry. - Carefully edited to ensure a consistent style, level, and approach throughout. Topics include innovative Phase I and II designs, trials in immune-oncology, rare diseases, and much more. [/content] [content title="Content"] [/content] [content title="Author(s)"] [/content] [/tab]
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